Editorial choices are almost seldom reversed. Authors who believe their article was rejected owing to a misunderstanding or error may, however, email the editorial office to clarify why they believe the decision was incorrect. A difference of opinion about the manuscript's interest, uniqueness, or fitness for the journal is not a valid reason for an appeal. Appeals must include meaningful new information immediately bearing on the decision (e.g., a well-reasoned argument demonstrating that a key critique in the rejection letter was based on erroneous or outdated information).

The appeal will be considered by the Editor In Chief and other relevant editors. The response of the journal to the appeal will be final. Even if the journal agrees to reconsider the manuscript, acceptance is not guaranteed, and the reconsideration process may involve previous or new reviewers or editors and substantive revision.